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Nonprofits Leading the Way in LGBTQ+ Rights


MissionEB exists to highlight the organizations that don’t just do good—but do it with intention. In this roundup, we’re spotlighting ten nonprofits that are boldly championing LGBTQ+ rights through legal advocacy, inclusive healthcare, and life-saving crisis support. These groups are actively hiring, deeply mission-driven, and offer workplace cultures where authenticity and passion are celebrated. Whether you’re in communications, operations, policy, healthcare, or tech—your next career move could start here.


🏳️‍🌈 Careers in Health Equity, Legal Advocacy & Crisis Support



Lambda Legal

Lambda Legal is the oldest and largest national legal organization dedicated to achieving full civil rights for LGBTQ+ people and everyone living with HIV. Through strategic litigation, public education, and policy advocacy, they have helped shape landmark legal decisions that impact millions. Culturally, Lambda is home to mission-minded attorneys, strategists, and change agents who are deeply committed to equity and justice. They foster a collaborative, high-impact environment that values both professional excellence and lived experience.




The Trevor Project

The Trevor Project is the world’s largest suicide prevention and mental health organization for LGBTQ+ youth. Known for their 24/7 crisis hotline, text, and chat services, Trevor also leads research, advocacy, and education initiatives aimed at creating a safer world for young queer people. The organization offers remote and hybrid roles, and its culture is built on empathy, transparency, and belonging. Teams are encouraged to bring their whole selves to work—creating a psychologically safe space for innovation and care.




GLMA: Health Professionals Advancing LGBTQ+ Equality

GLMA brings together healthcare professionals across disciplines to improve health outcomes for LGBTQ+ patients. With a focus on education, research, and policy reform, GLMA promotes culturally competent care while advocating for LGBTQ+ inclusion within the medical community. Employees and volunteers are passionate about health equity and bring a public health lens to their work. The culture emphasizes collaboration, community, and professional development, making it an ideal workplace for those with clinical or advocacy backgrounds.




OutRight Action International

Operating on a global scale, OutRight Action International works to advance human rights for LGBTQ+ people worldwide through UN engagement, international policy, and grassroots partnerships. Their team spans continents and languages, fostering an inclusive, cross-cultural environment where staff are empowered to lead in their own regions. The workplace culture supports deep collaboration, bold activism, and intellectual rigor—welcoming professionals in human rights, communications, legal policy, and development.




Callen-Lorde Community Health Center

Callen-Lorde is a New York-based health center that has become a national model for LGBTQ+ affirmative healthcare. They provide medical, behavioral, and dental services with dignity and without judgment—regardless of ability to pay. With a diverse staff that mirrors the community they serve, Callen-Lorde creates an affirming, welcoming work environment for clinicians, administrators, and support staff alike. Their commitment to both patient care and public health advocacy makes this a fulfilling place to grow a mission-driven career.





Trans Lifeline

Trans Lifeline is a peer support and crisis hotline run entirely by and for trans people. More than just a crisis line, they offer microgrants and advocacy programs that empower trans individuals with tangible resources. Their workplace is proudly remote, values mutual aid and lived experience, and centers trauma-informed principles in every facet of the organization. Roles here often blend direct service with movement-building—perfect for those who want to effect change from the inside out.




National Center for Transgender Equality (NCTE)

NCTE leads powerful public policy efforts to advance transgender equality. From DMV policies to healthcare protections to ID rights, NCTE’s work is systemic, urgent, and deeply human. Their team is made up of policy experts, community organizers, and communicators who operate with an activist heart and a strategist's mind. The culture is fast-moving but deeply values self-care and flexibility. Employees are encouraged to bring both their expertise and identities to the table.




Point Foundation

Point Foundation empowers LGBTQ+ students through scholarships, mentorship, and leadership training. Focused on the next generation of changemakers, the organization bridges financial support with community-building opportunities. Staff are passionate about education equity and often come from backgrounds in nonprofit leadership, student services, and youth engagement. The work environment is inclusive, affirming, and family-like—ideal for people who find purpose in mentoring and education.




SAGE (Services & Advocacy for GLBT Elders)

SAGE is the country’s largest and oldest organization dedicated to improving the lives of LGBTQ+ older adults. They offer housing, social services, training, and advocacy—combating isolation and ageism within LGBTQ+ communities. The culture is rooted in respect, storytelling, and compassion, with a strong focus on intersectional inclusion. It’s a fantastic home for professionals in social work, elder care, operations, and DEI.




Equality Federation

Equality Federation supports and strengthens state-based LGBTQ+ organizations across the U.S. by providing strategic support, leadership development, and policy tools. If you believe in the power of local action to drive national change, this is your kind of organization. The culture is entrepreneurial, progressive, and people-centered—valuing curiosity, collaboration, and courage. They seek professionals with backgrounds in organizing, policy, communications, and coalition building.


🔗 Jobs



Lead the Way for LGBTQ+ Rights

Whether your passion is health equity, crisis response, legal advocacy, or leadership development, these nonprofits are leading the way—and they need people like you. Each one offers fulfilling work, real community impact, and a place where your voice matters.


➡️ Explore even more mission-driven career paths at MissionEB.com and check out our weekly roundup of mission-driven job opportunities.

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